Results: Moisture content ranged from 64.10☐.57% (okra sauce) to 64.62☐.66% (lettuce sauce) did not differ significantly (p<0.05). ANOVA was used in comparing the means while turkey test was used in separating the means using Statistical product for service solution (SPSS) version 22.0. Results were expressed in means, standard deviation and percentages. The glycemic index and load was calculated per serving. Postprandial plasma glucose was measured at 0, 15, 30, 45, 60, 90 and 120 minutes. Subjects consumed a serving portion of vegetable sauce containing 25g of digestible carbohydrate. Thirty-six non-diabetic undergraduate students of Imo State University, Nigeria were selected after diabetes screening using oral glucose tolerance test (OGTT), glycated hemoglobin, anthropometric indices, blood pressure and other exclusion criteria. Proximate and dietary fibre analysis was carried out on the test food (okra, African spinach and lettuce sauces) and reference food (white bread). Methods: The recipe for the test food was developed and standardized. The use of locally made foods has been advocated for in the management of diabetes mellitus in recent times. In conclusion, dietary polysaccharides can effectively ameliorate hyperglycemia, hyperlipidemia, low-grade inflammation, and oxidative stress in type 2 diabetes mellitus (T2DM), and, thus, consumption of polysaccharides can be a valuable choice for diabetic control.īackground: Diet-related chronic disease especially diabetes mellitus, cardiovascular disease (CVDs), obesity, hypertension and cancers is a major public health problem in Nigeria. It enhances insulin signaling pathways through insulin receptors and activates the PI3K/Akt pathway, and eventually modulates ERK/JNK/MAPK pathway. In vivo and in vitro trials have revealed that treatment of these polysaccharides has hypoglycemic, hypolipidemic, antioxidant, and anti-inflammatory effects, which enhance pancreatic β-cell mass and alleviates β-cell dysfunction. The analysis of literature and appropriate data on anti-diabetic polysaccharide from electronic databases was conducted. Hence, this review summarizes the effects of dietary polysaccharides on diabetes and underlying molecular mechanisms related to inflammatory factors, oxidative stress, and diabetes in various animal models.

Dietary polysaccharides mainly derive from natural sources, including medicinal plants, grains, fruits, vegetables, edible mushroom, and medicinal foods, and possess anti-diabetic potential.

Currently, commercial diabetic drugs are clinically managed for diabetic treatment that has definite side effects. Diabetes mellitus is a multifactorial, heterogeneous metabolic disorder, causing various health complications and economic issues, which apparently impacts the human's life.

Boiled okra